The Michigan Wolverines have had the upper hand against the Ohio State Buckeyes as they own a 58-51-6 record in the all-time series. However, Ohio State has dominated of late, winning eight consecutive meetings and 15 of the last 16. After the 2020 matchup between the Big Ten Conference rivals was canceled due to COVID-19 issues within the Michigan program, the 117th installment of “The Game” takes place when the Wolverines (10-1, 7-1) host the Buckeyes (10-1, 8-0) on Saturday. Ohio State rolled past Michigan State 56-7 last week for its ninth victory in a row, while Michigan posted its third straight win by trouncing Maryland 59-18 on the road.

Kickoff at Michigan Stadium in Ann Arbor is set for noon ET. The Buckeyes are seven-point favorites in the latest Ohio State vs. Michigan odds from Caesars Sportsbook, while the over-under for total points scored is 64.5. Before making any Michigan vs. Ohio State picks or college football predictions, you need to see what the red-hot SportsLine Projection Model has to say.

The model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Ohio State vs. Michigan and just locked in its picks and predictions. You can visit SportsLine now to see the model’s picks. Here are the college football odds and betting lines for Michigan vs. Ohio State: 

• Ohio State vs. Michigan spread: Buckeyes -7
• Ohio State vs. Michigan over-under: 64.5 points 
• Ohio State vs. Michigan money line: Buckeyes -290, Wolverines +235
• OSU: The Buckeyes are 6-2 against the spread in their last eight visits to Ann Arbor 
• MICH: The Wolverines are 1-6 ATS in their last seven games against teams with winning records

Why Ohio State can cover

The Buckeyes just don’t lose conference games anymore, as they have won 23 consecutive contests against Big Ten rivals since suffering a 49-20 loss at Purdue on Oct. 20, 2018. In addition, they own a 21-game winning streak versus ranked conference opponents. Ohio State also has won all 13 of its true road games since the setback at Purdue and 12 straight meetings with ranked opponents away from home.

Redshirt freshman quarterback C.J. Stroud is coming off his fourth 400-yard performance of the season and ranks eighth in the nation in both passing yards (3,468) and completion percentage (71.1) while tying for fourth in touchdown tosses (36). Chris Olave is tied for second in the country as he has hauled in 13 of those scoring passes, including 11 during his current eight-game streak, and is coming off his fifth 100-yard effort of the year as he gained 140 on seven catches against the Spartans. Freshman TreVeyon Henderson has run for a TD in eight of his 11 games and is tied for 10th in the nation with 14 rushing touchdowns while ranking 19th with 1,098 yards on the ground.

Why Michigan can cover

Michigan is no slouch offensively, as it ranks 15th in the country in both rushing (218.4 yards) and scoring (36.9 points). The Wolverines amassed 503 total yards in last week’s 59-18 triumph at Maryland, which marked the eighth time this season they have eclipsed the 30-point mark. They proved capable of scoring in many fashions, rushing for three touchdowns and passing for a trio while returning both a kickoff and an interception for scores.

The Wolverines’ ground attack is led by Hassan Haskins, who ran for 78 yards against the Terrapins while posting his fifth two-touchdown performance of the season. The senior is 23rd in the country with 1,063 rushing yards and tied for 16th with 13 TD runs. Michigan hopes to get back sophomore Blake Corum, who has recorded 778 yards and 10 touchdowns but has missed the last two games with a high-ankle sprain.

How to make Ohio State vs. Michigan picks

SportsLine’s model is leaning under on the total, projecting the teams to combine for 64 points. It also has generated an against-the-spread pick that cashes in over 60 percent of simulations. You can only get the model’s Michigan vs. Ohio State pick at SportsLine.

So who wins Michigan vs. Ohio State? And which side of the spread hits over 60 percent of the time? Visit SportsLine now to see which side of the Ohio State vs. Michigan spread to back, all from the advanced model that is up almost $3,700 on its top-rated college football spread picks, and find out.