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Ohio State vs. Michigan odds, line: 2021 college football picks, Week 13 predictions, bets from proven model

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The Michigan Wolverines have had the upper hand against the Ohio State Buckeyes as they own a 58-51-6 record in the all-time series. However, Ohio State has dominated of late, winning eight consecutive meetings and 15 of the last 16. After the 2020 matchup between the Big Ten Conference rivals was canceled due to COVID-19 issues within the Michigan program, the 117th installment of “The Game” takes place when the Wolverines (10-1, 7-1) host the Buckeyes (10-1, 8-0) on Saturday. Ohio State rolled past Michigan State 56-7 last week for its ninth victory in a row, while Michigan posted its third straight win by trouncing Maryland 59-18 on the road.

Kickoff at Michigan Stadium in Ann Arbor is set for noon ET. The Buckeyes are seven-point favorites in the latest Ohio State vs. Michigan odds from Caesars Sportsbook, while the over-under for total points scored is 64.5. Before making any Michigan vs. Ohio State picks or college football predictions, you need to see what the red-hot SportsLine Projection Model has to say.

The model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

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Now, the model has set its sights on Ohio State vs. Michigan and just locked in its picks and predictions. You can visit SportsLine now to see the model’s picks. Here are the college football odds and betting lines for Michigan vs. Ohio State: 

  • Ohio State vs. Michigan spread: Buckeyes -7
  • Ohio State vs. Michigan over-under: 64.5 points 
  • Ohio State vs. Michigan money line: Buckeyes -290, Wolverines +235
  • OSU: The Buckeyes are 6-2 against the spread in their last eight visits to Ann Arbor 
  • MICH: The Wolverines are 1-6 ATS in their last seven games against teams with winning records

Featured Game | Michigan Wolverines vs. Ohio State Buckeyes

Why Ohio State can cover

The Buckeyes just don’t lose conference games anymore, as they have won 23 consecutive contests against Big Ten rivals since suffering a 49-20 loss at Purdue on Oct. 20, 2018. In addition, they own a 21-game winning streak versus ranked conference opponents. Ohio State also has won all 13 of its true road games since the setback at Purdue and 12 straight meetings with ranked opponents away from home.

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Redshirt freshman quarterback C.J. Stroud is coming off his fourth 400-yard performance of the season and ranks eighth in the nation in both passing yards (3,468) and completion percentage (71.1) while tying for fourth in touchdown tosses (36). Chris Olave is tied for second in the country as he has hauled in 13 of those scoring passes, including 11 during his current eight-game streak, and is coming off his fifth 100-yard effort of the year as he gained 140 on seven catches against the Spartans. Freshman TreVeyon Henderson has run for a TD in eight of his 11 games and is tied for 10th in the nation with 14 rushing touchdowns while ranking 19th with 1,098 yards on the ground.

Why Michigan can cover

Michigan is no slouch offensively, as it ranks 15th in the country in both rushing (218.4 yards) and scoring (36.9 points). The Wolverines amassed 503 total yards in last week’s 59-18 triumph at Maryland, which marked the eighth time this season they have eclipsed the 30-point mark. They proved capable of scoring in many fashions, rushing for three touchdowns and passing for a trio while returning both a kickoff and an interception for scores.

The Wolverines’ ground attack is led by Hassan Haskins, who ran for 78 yards against the Terrapins while posting his fifth two-touchdown performance of the season. The senior is 23rd in the country with 1,063 rushing yards and tied for 16th with 13 TD runs. Michigan hopes to get back sophomore Blake Corum, who has recorded 778 yards and 10 touchdowns but has missed the last two games with a high-ankle sprain.

How to make Ohio State vs. Michigan picks

SportsLine’s model is leaning under on the total, projecting the teams to combine for 64 points. It also has generated an against-the-spread pick that cashes in over 60 percent of simulations. You can only get the model’s Michigan vs. Ohio State pick at SportsLine.

So who wins Michigan vs. Ohio State? And which side of the spread hits over 60 percent of the time? Visit SportsLine now to see which side of the Ohio State vs. Michigan spread to back, all from the advanced model that is up almost $3,700 on its top-rated college football spread picks, and find out.

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How to watch Appalachian State vs. James Madison: NCAA Football live stream info, TV channel, time, game odds

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Who’s Playing

James Madison @ Appalachian State

Current Records: James Madison 2-0; Appalachian State 2-1

What to Know

The James Madison Dukes watched the action from their couches last weekend, but are set to take to the field. James Madison and the Appalachian State Mountaineers will face off in a Sun Belt battle at 3:30 p.m. ET Saturday at Kidd Brewer Stadium. The odds don’t look promising for the Dukes, but the bigger the opponent is, the harder they fall.

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A well-balanced attack led James Madison over the Norfolk State Spartans every single quarter on their way to victory two weeks ago. James Madison claimed a resounding 63-7 win over Norfolk State at home. The game was pretty much decided by the half, when the score had already reached 35 to nothing.

Meanwhile, Appalachian State didn’t have too much breathing room in their contest with the Troy Trojans last week, but they still walked away with a 32-28 victory. Appalachian State QB Chase Brice was slinging it as he passed for two TDs and 279 yards on 34 attempts. Near the top of the highlight reel was Brice’s 53-yard TD bomb to WR Christan Horn in the fourth quarter.

Their wins bumped the Dukes to 2-0 and the Mountaineers to 2-1. Watch the matchup and check back on CBS Sports to find out who keeps up the positive energy and who hits a stumbling block.

How To Watch

  • When: Saturday at 3:30 p.m. ET
  • Where: Kidd Brewer Stadium — Boone, North Carolina
  • TV: ESPN Plus
  • Online streaming: fuboTV (Try for free. Regional restrictions may apply.)
  • Follow: CBS Sports App
  • Ticket Cost: $40.99

Odds

The Mountaineers are a solid 6.5-point favorite against the Dukes, according to the latest college football odds.

The oddsmakers had a good feel for the line for this one, as the game opened with the Mountaineers as a 7.5-point favorite.

Over/Under: -111

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See college football picks for every single game, including this one, from SportsLine’s advanced computer model. Get picks now.

Series History

This is the first time these teams have played each other within the last seven years.



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UTSA vs. Texas Southern: How to watch NCAA Football online, TV channel, live stream info, game time

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Who’s Playing

Texas Southern @ UTSA

Current Records: Texas Southern 1-2; UTSA 1-2

What to Know

The Texas Southern Tigers will take on the UTSA Roadrunners at 3:30 p.m. ET Saturday at Alamodome. Texas Southern isn’t favored, but they just beat the odds in their last game, so don’t count them out.

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The Tigers kept a clean sheet against the Southern University Jaguars last week and took the matchup 24 to nothing. The squad ran away with 21 points in the first half and mostly just sat on those in the second to pick up the victory.

Meanwhile, it was all tied up 17-17 at halftime, but UTSA was not quite the Texas Longhorns’ equal in the second half when they met last week. The Roadrunners suffered a grim 41-20 defeat to the Longhorns. This contest was a close 17-17 at the break, but unfortunately for UTSA it sure didn’t stay that way. A silver lining for them was the play of RB Brenden Brady, who threw one touchdown in addition to punching in one rushing touchdown.

Texas Southern’s win lifted them to 1-2 while UTSA’s loss dropped them down to 1-2. We’ll find out if the Tigers can add another positive mark to their record or if UTSA can shake off the defeat and take the spring out of Texas Southern’s step.

How To Watch

  • When: Saturday at 3:30 p.m. ET
  • Where: Alamodome — San Antonio, Texas
  • TV: STADIUM
  • Follow: CBS Sports App
  • Ticket Cost: $69.00

Odds

The Roadrunners are a big 42-point favorite against the Tigers, according to the latest college football odds.

Bettors have moved against the Roadrunners slightly, as the game opened with the Roadrunners as a 44-point favorite.

Over/Under: -110

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See college football picks for every single game, including this one, from SportsLine’s advanced computer model. Get picks now.

Series History

This is the first time these teams have played each other within the last seven years.



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North Carolina vs. Notre Dame live stream info, TV channel: How to watch NCAA Football on TV, stream online

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Who’s Playing

Notre Dame @ North Carolina

Current Records: Notre Dame 1-2; North Carolina 3-0

What to Know

The North Carolina Tar Heels will be returning home after a two-game road trip. They will take on the Notre Dame Fighting Irish at 3:30 p.m. ET Saturday at Kenan Memorial Stadium after a week off. UNC is expected to win — but not by much — so they will need to come into the game prepared for a fight.

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The Tar Heels beat the Georgia State Panthers 35-28 two weeks ago. Among those leading the charge for UNC was RB Omarion Hampton, who rushed for two TDs and 110 yards on 16 carries. Hampton put himself on the highlight reel with a 58-yard TD scramble in the third quarter.

Meanwhile, Notre Dame netted a 24-17 victory over the California Golden Bears last week. RB Audric Estime and RB Chris Tyree were among the main playmakers for Notre Dame as the former punched in one rushing touchdown and the latter snatched one receiving TD.

Notre Dame’s defense was a presence as well, as it embarrassed California’s offensive line to sack QB Jack Plummer six times for a total loss of 47 yards. It was a group effort with four guys contributing.

The wins brought the Tar Heels up to 3-0 and the Fighting Irish to 1-2. A pair of stats to keep an eye on: UNC enters the matchup with 310 passing yards per game on average, good for 21st best in the nation. But Notre Dame comes into the contest boasting the 34th fewest passing yards allowed per game in the nation at 184. These opposing strengths should make for an exciting matchup.

How To Watch

  • When: Saturday at 3:30 p.m. ET
  • Where: Kenan Memorial Stadium — Chapel Hill, North Carolina
  • TV: ABC
  • Online streaming: fuboTV (Try for free. Regional restrictions may apply.)
  • Follow: CBS Sports App
  • Ticket Cost: $110.00

Odds

The Tar Heels are a slight 2.5-point favorite against the Fighting Irish, according to the latest college football odds.

The line on this game has moved quite a bit since it opened, as it started out with the Fighting Irish as a 1.5-point favorite.

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Over/Under: -110

See college football picks for every single game, including this one, from SportsLine’s advanced computer model. Get picks now.

Series History

Notre Dame have won all of the games they’ve played against North Carolina in the last eight years.

  • Oct 30, 2021 – Notre Dame 44 vs. North Carolina 34
  • Nov 27, 2020 – Notre Dame 31 vs. North Carolina 17
  • Oct 07, 2017 – Notre Dame 33 vs. North Carolina 10



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