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Kentucky vs. Vanderbilt odds, line, spread: 2021 college football picks, Week 11 predictions from proven model

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The Vanderbilt Commodores (2-7) host the Kentucky Wildcats (6-3) in an SEC clash at 7 p.m. ET on Saturday at Vanderbilt Stadium. Both teams are looking to snap losing streaks. Kentucky is currently on a three-game slide after starting the season 6-0. Vanderbilt has dropped four straight since beating UConn in early October. 

Kentucky is favored by 21 points in the latest Vanderbilt vs. Kentucky odds from Caesars Sportsbook, and the over-under is set at 52.5. Before making any Kentucky vs. Vanderbilt picks, you need to check out the college football predictions and betting advice from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 11 of the 2021 season on a 31-20 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

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Now, the model has set its sights on Vanderbilt vs. Kentucky and just revealed its coveted CFB picks and predictions. You can head to SportsLine now to see the model’s picks. Here are several college football odds and betting lines for Vanderbilt vs. Kentucky:

  • Vanderbilt vs. Kentucky spread: Vanderbilt +21
  • Vanderbilt vs. Kentucky over-under: 52.5 points
  • Vanderbilt vs. Kentucky money line: Kentucky -1700, Vanderbilt +900

Featured Game | Vanderbilt Commodores vs. Kentucky Wildcats

What you need to know about Vanderbilt

Vanderbilt came up short against the Missouri Tigers last week, falling 37-28. Despite the loss, Vanderbilt got a solid performance out of quarterback Mike Wright, who threw for 122 yards and three touchdowns in addition to picking up 152 yards on the ground. 

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The Commodores’ struggles continue, with their SEC losing streak now up to 18 games. Vanderbilt’s last conference win came on October 19, 2019 against Missouri. Vanderbilt’s issues have come on both sides of the ball. Offensively, the Commodores have averaged just 301.2 total yards and 14.9 points per game. Defensively, the Commodores are giving up 463.1 yards and 35.6 points per game. 

What you need to know about Kentucky

Meanwhile, it was close but no cigar for the Wildcats as they fell 45-42 to the Tennessee Volunteers on Saturday. That makes it the first time this season Kentucky has let down its home crowd. A silver lining for Kentucky was the play of quarterback Will Levis, who passed for 369 yards and three TDs on 49 attempts, in addition to rushing for 47 yards and two touchdowns.

The Wildcats’ explosive offensive should have a field day against Vanderbilt’s defense. Running back Chris Rodriguez Jr. is one of the premier ball carriers in the SEC, and Vanderbilt’s defense is giving up 184.6 yards per game and an average of 5.3 yards per carry. Look for Kentucky to try and take out the frustrations of its three-game losing streak on Saturday night.

How to make Vanderbilt vs. Kentucky picks

The model has simulated Vanderbilt vs. Kentucky 10,000 times and the results are in. We can tell you that the model is leaning under on the point total, and it’s also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the model’s Kentucky vs. Vanderbilt picks at SportsLine.

So who wins Kentucky vs. Vanderbilt? And which side of the spread in nearly 60 percent of the time? Visit SportsLine now to see which side of the spread you need to be all over, all from the model that has crushed its college football picks, and find out. 

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How to watch Appalachian State vs. James Madison: NCAA Football live stream info, TV channel, time, game odds

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Who’s Playing

James Madison @ Appalachian State

Current Records: James Madison 2-0; Appalachian State 2-1

What to Know

The James Madison Dukes watched the action from their couches last weekend, but are set to take to the field. James Madison and the Appalachian State Mountaineers will face off in a Sun Belt battle at 3:30 p.m. ET Saturday at Kidd Brewer Stadium. The odds don’t look promising for the Dukes, but the bigger the opponent is, the harder they fall.

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A well-balanced attack led James Madison over the Norfolk State Spartans every single quarter on their way to victory two weeks ago. James Madison claimed a resounding 63-7 win over Norfolk State at home. The game was pretty much decided by the half, when the score had already reached 35 to nothing.

Meanwhile, Appalachian State didn’t have too much breathing room in their contest with the Troy Trojans last week, but they still walked away with a 32-28 victory. Appalachian State QB Chase Brice was slinging it as he passed for two TDs and 279 yards on 34 attempts. Near the top of the highlight reel was Brice’s 53-yard TD bomb to WR Christan Horn in the fourth quarter.

Their wins bumped the Dukes to 2-0 and the Mountaineers to 2-1. Watch the matchup and check back on CBS Sports to find out who keeps up the positive energy and who hits a stumbling block.

How To Watch

  • When: Saturday at 3:30 p.m. ET
  • Where: Kidd Brewer Stadium — Boone, North Carolina
  • TV: ESPN Plus
  • Online streaming: fuboTV (Try for free. Regional restrictions may apply.)
  • Follow: CBS Sports App
  • Ticket Cost: $40.99

Odds

The Mountaineers are a solid 6.5-point favorite against the Dukes, according to the latest college football odds.

The oddsmakers had a good feel for the line for this one, as the game opened with the Mountaineers as a 7.5-point favorite.

Over/Under: -111

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See college football picks for every single game, including this one, from SportsLine’s advanced computer model. Get picks now.

Series History

This is the first time these teams have played each other within the last seven years.



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UTSA vs. Texas Southern: How to watch NCAA Football online, TV channel, live stream info, game time

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Who’s Playing

Texas Southern @ UTSA

Current Records: Texas Southern 1-2; UTSA 1-2

What to Know

The Texas Southern Tigers will take on the UTSA Roadrunners at 3:30 p.m. ET Saturday at Alamodome. Texas Southern isn’t favored, but they just beat the odds in their last game, so don’t count them out.

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The Tigers kept a clean sheet against the Southern University Jaguars last week and took the matchup 24 to nothing. The squad ran away with 21 points in the first half and mostly just sat on those in the second to pick up the victory.

Meanwhile, it was all tied up 17-17 at halftime, but UTSA was not quite the Texas Longhorns’ equal in the second half when they met last week. The Roadrunners suffered a grim 41-20 defeat to the Longhorns. This contest was a close 17-17 at the break, but unfortunately for UTSA it sure didn’t stay that way. A silver lining for them was the play of RB Brenden Brady, who threw one touchdown in addition to punching in one rushing touchdown.

Texas Southern’s win lifted them to 1-2 while UTSA’s loss dropped them down to 1-2. We’ll find out if the Tigers can add another positive mark to their record or if UTSA can shake off the defeat and take the spring out of Texas Southern’s step.

How To Watch

  • When: Saturday at 3:30 p.m. ET
  • Where: Alamodome — San Antonio, Texas
  • TV: STADIUM
  • Follow: CBS Sports App
  • Ticket Cost: $69.00

Odds

The Roadrunners are a big 42-point favorite against the Tigers, according to the latest college football odds.

Bettors have moved against the Roadrunners slightly, as the game opened with the Roadrunners as a 44-point favorite.

Over/Under: -110

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See college football picks for every single game, including this one, from SportsLine’s advanced computer model. Get picks now.

Series History

This is the first time these teams have played each other within the last seven years.



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North Carolina vs. Notre Dame live stream info, TV channel: How to watch NCAA Football on TV, stream online

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Who’s Playing

Notre Dame @ North Carolina

Current Records: Notre Dame 1-2; North Carolina 3-0

What to Know

The North Carolina Tar Heels will be returning home after a two-game road trip. They will take on the Notre Dame Fighting Irish at 3:30 p.m. ET Saturday at Kenan Memorial Stadium after a week off. UNC is expected to win — but not by much — so they will need to come into the game prepared for a fight.

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The Tar Heels beat the Georgia State Panthers 35-28 two weeks ago. Among those leading the charge for UNC was RB Omarion Hampton, who rushed for two TDs and 110 yards on 16 carries. Hampton put himself on the highlight reel with a 58-yard TD scramble in the third quarter.

Meanwhile, Notre Dame netted a 24-17 victory over the California Golden Bears last week. RB Audric Estime and RB Chris Tyree were among the main playmakers for Notre Dame as the former punched in one rushing touchdown and the latter snatched one receiving TD.

Notre Dame’s defense was a presence as well, as it embarrassed California’s offensive line to sack QB Jack Plummer six times for a total loss of 47 yards. It was a group effort with four guys contributing.

The wins brought the Tar Heels up to 3-0 and the Fighting Irish to 1-2. A pair of stats to keep an eye on: UNC enters the matchup with 310 passing yards per game on average, good for 21st best in the nation. But Notre Dame comes into the contest boasting the 34th fewest passing yards allowed per game in the nation at 184. These opposing strengths should make for an exciting matchup.

How To Watch

  • When: Saturday at 3:30 p.m. ET
  • Where: Kenan Memorial Stadium — Chapel Hill, North Carolina
  • TV: ABC
  • Online streaming: fuboTV (Try for free. Regional restrictions may apply.)
  • Follow: CBS Sports App
  • Ticket Cost: $110.00

Odds

The Tar Heels are a slight 2.5-point favorite against the Fighting Irish, according to the latest college football odds.

The line on this game has moved quite a bit since it opened, as it started out with the Fighting Irish as a 1.5-point favorite.

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Over/Under: -110

See college football picks for every single game, including this one, from SportsLine’s advanced computer model. Get picks now.

Series History

Notre Dame have won all of the games they’ve played against North Carolina in the last eight years.

  • Oct 30, 2021 – Notre Dame 44 vs. North Carolina 34
  • Nov 27, 2020 – Notre Dame 31 vs. North Carolina 17
  • Oct 07, 2017 – Notre Dame 33 vs. North Carolina 10



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