The No. 8 seed North Carolina Tar Heels (28-9) and the No. 2 seed Duke Blue Devils (32-6) clash in the 2022 Final Four on Saturday. Duke head coach Mike Krzyzewski looks to advance to the title game in his last season coaching the program. This will be the first time these two universities square off in the NCAA Tournament. These teams split the season series 1-1. 

Tipoff is at 8:49 p.m. ET from New Orleans. Caesars Sportsbook lists the Blue Devils at -4 in the latest Duke vs. North Carolina odds in the 2022 NCAA Tournament. The over-under for total points is set at 151. Before making any North Carolina vs. Duke picks, be sure to check out the college basketball predictions and betting advice from SportsLine’s proven computer model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $1,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Duke vs. UNC and revealed its coveted picks and predictions for the Final Four 2022. You can head to SportsLine to see all of the model’s college basketball picks. Here are several college basketball odds and trends for UNC vs. Duke:

• Duke vs. North Carolina spread: Blue Devils -4
• Duke vs. North Carolina over-under: 151 points
• Duke vs. North Carolina money line: Tar Heels +160, Blue Devils -190
• UNC: The Tar Heels are 4-0 ATS in their last four games overall
• DUKE: The over is 7-1 in Blue Devils’ last eight games following a straight-up win

Why Duke can cover

Sophomore center Mark Williams is a physical presence down low for the Blue Devils. Williams is a solid rebounder and a terrific rim defender. The Virginia native averages 11.3 points, 7.5 rebounds and 2.9 blocks per game. He is also super-efficient, shooting 70 percent from the field. Williams posted 15-plus points and three-plus blocks in three of his last four outings. In the Sweet 16 victory over Texas Tech, Williams tallied 16 points, eight rebound and three blocks.

Freshman guard AJ Griffin is another scoring option in the frontcourt for Duke. Griffin is an athletic swingman with solid defense and with a smooth jumper. The New York native puts up 10.5 points, 3.9 rebounds and shoots 40 percent from downtown. Griffin has a solid frame and can defend multiple positions on the floor. In his last outing, he amassed 18 points, three rebounds, one block and went 7-for-9 from the field.  

Why North Carolina can cover

Sophomore Caleb Love is an aggressive scoring guard with a downhill play style. He attacks the lane with a quick first step to blow by defenders. Love averages 15.7 points, 3.4 rebounds and 3.7 assists per game. He is also a reliable threat on the perimeter, shooting 39 percent from three. The Missouri native has logged 20-plus points in two games during the tournament. On March 25 against UCLA, Love notched 30 points, three rebounds, four assists and made six 3-pointers.

Senior forward Brady Manek is a pick and pop threat with a sweet shooting stroke. Manek also uses his size score in the paint. The Oklahoma native logs 15.2 points, 5.9 rebounds and shoots 39 percent from three. He’s knocked down at least three 3-pointers in four straight games. In the second-round win over Baylor, Manek supplied 26 points, five rebounds and went 4-for-8 from downtown. 

How to make UNC vs. Duke picks

SportsLine’s model is leaning under on the total, projecting the teams to combine for 150 points. The model also says one side of the spread hits well over 50 percent of the time. You can only see the model’s pick at SportsLine.

So who wins Duke vs. North Carolina? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college basketball picks, and find out.