Rivalry week will go a long way in shaping the College Football Playoff field this season. The Week 13 college football odds from Caesars Sportsbook list Ohio State at -8 against Michigan, Oklahoma State at -3.5 against Oklahoma, Georgia at -35 against Georgia Tech and Alabama at -19.5 against Auburn in the 3:30 p.m. ET SEC on CBS game. All those Week 13 college football spreads should see plenty of action.

But with games on Tuesday, Thursday, Friday and Saturday, there are plenty of lines to consider, and some of the best values might come from games that are slightly off the radar. Who should you target in your Week 13 college football bets? Before making any Week 13 college football picks, be sure to see the latest college football predictions and betting advice from SportsLine’s proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Week 13 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top Week 13 college football predictions

One of the top college football picks the model is recommending for Week 13: Oklahoma State (-3.5) covers against Oklahoma in the Bedlam Series rivalry matchup at 7:30 p.m. ET on Saturday. The Cowboys are normally synonymous with offense, but they boast the top-ranked defense in the Big 12 this season. They’re also putting up 31.4 points per game, and the model sees that combination overwhelming an inconsistent OU squad.

A win in this one and a Big 12 title would be enough to put OSU squarely in the College Football Playoff conversation. The Cowboys have also been a tremendous team to back this season as they’re a sizzling 9-1 against the spread. SportsLine’s model shows them covering more than 60 percent of the time, making OSU a top pick for rivalry week college football bets.

Another one of the college football predictions from the model: Oregon (-7) bounces back and takes care of business against Oregon State in a 3:30 p.m. ET matchup on Saturday. The Ducks likely played themselves out of the playoff picture with that loss to Utah last week. But they can still wrap up the Pac-12 North with a win over their in-state rivals.

SportsLine’s model sees this as a two-score win for the Ducks as they pile up around 200 yards on the ground. Oregon covers almost 60 percent of the time, while the under (61) hits almost 60 percent of the time, making this game a solid parlay opportunity. 

How to make Week 13 college football picks 

The model has also made the call on who wins and covers in every other game on the Week 13 college football schedule, and it’s also calling for a top College Football Playoff contender to get a huge scare from a big underdog. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence? And which underdog do you need to jump on now? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,700 in profit over the past five-plus seasons, and find out.

Week 13 college football odds (via Caesars)

Here are the college football lines for some of Week 13’s most notable matchups:

Tuesday, Nov. 23

Buffalo vs. Ball State (-6.5, 58.5)

Western Michigan vs. Northern Illinois (+4, 62.5)

Featured Game | Northern Illinois Huskies vs. Western Michigan Broncos

Thursday, Nov. 25

Fresno State vs. San Jose State (+7.5, 52.5)

Featured Game | San Jose State Spartans vs. Fresno State Bulldogs

Ole Miss vs. Mississippi State (-1, 60.5)

Featured Game | Mississippi State Bulldogs vs. Ole Miss Rebels

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Friday, Nov. 26

Boise State vs. San Diego State (+2.5, 44)

Featured Game | San Diego State Aztecs vs. Boise State Broncos

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Iowa vs. Nebraska (-3.5, 44.5)

Featured Game | Nebraska Cornhuskers vs. Iowa Hawkeyes

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Missouri vs. Arkansas (-14, 62.5)

Featured Game | Arkansas Razorbacks vs. Missouri Tigers

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Cincinnati vs. East Carolina (+14, 58)

Featured Game | East Carolina Pirates vs. Cincinnati Bearcats

Colorado vs. Utah (-24, 52.5)

Featured Game | Utah Utes vs. Colorado Buffaloes

UNC vs. NC State (-7, 63)

Featured Game | NC State Wolfpack vs. North Carolina Tar Heels

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Saturday, Nov. 27

Wake Forest vs. Boston College (+5, 64.5)

Featured Game | Boston College Eagles vs. Wake Forest Demon Deacons

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Houston vs. UConn (+32.5, 57.5)

Featured Game | Connecticut Huskies vs. Houston Cougars

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Georgia vs. Georgia Tech (+35, 54.5)

Ohio State vs. Michigan (+8, 64)

Featured Game | Michigan Wolverines vs. Ohio State Buckeyes

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Texas Tech vs. Baylor (-14, 52)

Featured Game | Baylor Bears vs. Texas Tech Red Raiders

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UTSA vs. North Texas (+12, 59.5)

Featured Game | North Texas Mean Green vs. UTSA Roadrunners

Penn State vs. Michigan State (-1.5, 52.5)

Featured Game | Michigan State Spartans vs. Penn State Nittany Lions

Oregon State vs. Oregon (-7, 61)

Featured Game | Oregon Ducks vs. Oregon State Beavers

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Alabama vs. Auburn (+19.5, 55)

Featured Game | Auburn Tigers vs. Alabama Crimson Tide

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Wisconsin vs. Minnesota (+6.5, 39)

Featured Game | Minnesota Golden Gophers vs. Wisconsin Badgers

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Texas A&M vs. LSU (+6.5, 45.5)

Latest Odds:

LSU Tigers
+6.5

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Pittsburgh vs. Syracuse (+11, 58.5)

Featured Game | Syracuse Orange vs. Pittsburgh Panthers

Oklahoma vs. Oklahoma State (-3.5, 51.5)

Featured Game | Oklahoma State Cowboys vs. Oklahoma Sooners

Notre Dame vs. Stanford (+17, 52.5)

Featured Game | Stanford Cardinal vs. Notre Dame Fighting Irish

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BYU vs. USC (+7, 64)

Featured Game | USC Trojans vs. BYU Cougars

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